A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-21
Type miRNA
Species Rat Rattus
Tissue Colon
Experiment Method RT-PCR,Western blot
Up/Down Up
Pro/Anti NA
Funtion Description Aging accompanied by increased expression of miR-21 in colon. These increases are further increased in response to the colonic carcinogen dimethylhydrazine (DMH). Aging is also associated with increased tyrosine-phosphorylated epidermal growth factor rece
Regulation Gene NA
Year 2012
Pubmed ID 22281474
Title EGFR regulation of colon cancer stem-like cells during aging and in response to the colonic carcinogen dimethylhydrazine
Drug dimethylhydrazine (DMH)
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA