A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-214
Type miRNA
Species Homo sapiens
Tissue NSCLC cell lines H23, A549, H157, H661, H1299 and U-1810 and the SCLC cell lines H69, H82, U-1285, U-1690 and U-1906
Experiment Method qRT-PCR
Up/Down Up
Pro/Anti Anti
Funtion Description Suppression of miRNA-214 expression sensitises NSCLC cells to IR through induction of senescence Morphological evaluation of U-1810 cells after knockdown of miRNA-214 expression in combination with IR revealed an elongated phenotype resembling cellular se
Regulation Gene NA
Year 2012
Pubmed ID 22929890
Title miRNA-214 modulates radiotherapy response of non-small cell lung cancer cells through regulation of p38MAPK, apoptosis and senescence
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA