| Name |
miR-21-5p
|
| Type |
miRNA
|
| Species |
Mus musculus
|
| Tissue |
NA
|
| Experiment Method |
Real-time PCR,Western blot ,Luciferase reporter gene assay
|
| Up/Down |
Up
|
| Pro/Anti |
Pro
|
| Funtion Description |
miR21-5p/203a-3p promote ox-LDL-induced endothelial senescence through down-regulation of Drp1 in a direct or indirect way.
|
| Regulation Gene |
Drp1
|
| Year |
2017
|
| Pubmed ID |
28347692
|
| Title |
miR-21-5p/203a-3p promote ox-LDL-induced endothelial cell senescence through down-regulation of mitochondrial fission protein Drp1.
|
| Drug |
ox-LDL
|
| Disease |
hyperlipidemic
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|