Details
| Name | miR-217 |
| Type | miRNA |
| Species | Homo sapiens |
| Tissue | HUVECs |
| Experiment Method | RT-PCR,Northern Blot |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | miR-217 inhibits SirT1 expression through a miR-217-binding site within the 3'-UTR of SirT1. In young human umbilical vein endothelial cells, human aortic endothelial cells, and human coronary artery endothelial cells, miR-217 induces a premature senescen |
| Regulation Gene | SirT1 |
| Year | 2009 |
| Pubmed ID | 19786632 |
| Title | MicroRNA 217 Modulates Endothelial Cell Senescence via Silent Information Regulator 1 |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |