A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-219a-5p
Type miRNA
Species Homo sapiens
Tissue NA
Experiment Method qPCR,Rorb-3'UTR luciferase report construct and assay
Up/Down Down
Pro/Anti NA
Funtion Description miR-219a-5p regulates Rorb levels in osteoblasts and bone, and that miR-219a-5p could represent a novel tool to suppress Rorb activity and promote bone anabolism in the context of age-related bone disorders, such as osteoporosis.
Regulation Gene Rorb
Year 2019
Pubmed ID 30321475
Title miR-219a-5p Regulates RorB During Osteoblast Differentiation and in Age-related Bone Loss
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA