Details
| Name | miR-22 |
| Type | miRNA |
| Species | Mus musculus |
| Tissue | Liver |
| Experiment Method | qRT-PCR |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | XFE progeroid syndrome, a disease of accelerated aging caused by deficiency in the DNA repair endonuclease XPF-ERCC1, is modeled by Ercc1 knockout and hypomorphic mice. The miRNA expression regulator Dicer is significantly downregulated in tissues of old |
| Regulation Gene | NA |
| Year | 2013 |
| Pubmed ID | 23852002 |
| Title | Identification of microRNAs dysregulated in cellular senescence driven by endogenous genotoxic stress |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |