Details
| Name | miR-22 |
| Type | miRNA |
| Species | Homo sapiens |
| Tissue | MRC-5 |
| Experiment Method | RT-PCR,Southern blot |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | miR-22 is up-regulated in human senescent fibroblasts and epithelial cells but down-regulated in various cancer cell lines. miR-22 overexpression induces growth suppression and acquisition of a senescent phenotype in human normal and cancer cells. miR-22 |
| Regulation Gene | CDK6;SIRT1;Sp1 |
| Year | 2011 |
| Pubmed ID | 21502362 |
| Title | miR-22 represses cancer progression by inducing cellular senescence |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |