| Name |
miR-24
|
| Type |
miRNA
|
| Species |
Homo sapiens
|
| Tissue |
NA
|
| Experiment Method |
Senescence-associated beta-galactosidase staining (SA-B-gal),Western blot,real-time PCR
|
| Up/Down |
NA
|
| Pro/Anti |
Pro
|
| Funtion Description |
In summary, mir-24 activity appears to propagate senescence induction, as shown by enforced overexpression which promoted oxidative-stress induced premature senescence. In keeping with these observations, it can be reasoned that the expression of DNA topo
|
| Regulation Gene |
TOP1
|
| Year |
2016
|
| Pubmed ID |
26748253
|
| Title |
mir-24 activity propagates stress-induced senescence by down regulating DNA topoisomerase 1.
|
| Drug |
H2O2
|
| Disease |
NA
|
| Environment Factors |
oxidation
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|