| Name |
miR-26b
|
| Type |
miRNA
|
| Species |
Mus musculus
|
| Tissue |
NA
|
| Experiment Method |
RT-qPCR,Western blot,ELISA,Luciferase assay
|
| Up/Down |
Up
|
| Pro/Anti |
NA
|
| Funtion Description |
As IGF-1 is critical in AB formation, increasing IGF-1 expression levels is suggested as a potential therapeutic strategy for AD. Results of the present study suggest that miR-26b is a potential therapeutic target for the downregulation of AB formation.
|
| Regulation Gene |
IGF-1
|
| Year |
2016
|
| Pubmed ID |
26847596
|
| Title |
MicroRNA26b is upregulated in a double transgenic mouse model of Alzheimer's disease and promotes the expression of amyloidB by targeting insulinlike growth factor 1
|
| Drug |
NA
|
| Disease |
Alzheimer's disease
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|