Details
| Name | CDC42 |
| Type | gene |
| Species | Mus musculus |
| Tissue | bone marrow |
| Experiment Method | RT-PCR;Western blot |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | By using two FA mouse models, here we have investigated the hematopoiesis-supportive function of FA BM mesenchymal stroma cells (MSCs). We found that MSCs deficient for Fanca or Fancc gene are defective in proliferation and prone to undergo senescence in |
| Regulation Gene | NA |
| Year | 2018 |
| Pubmed ID | 29377497 |
| Title | Reduced Cdc42 activity compromises hematopoiesis-supportive function of Fanconi anemia mesenchymal stromal cells |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |