A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-29
Type miRNA
Species Mus musculus
Tissue HEK-293T,U2OS,p53-deficient cells
Experiment Method qPCR,Immunoblot,cell infection,Immunofluorescence
Up/Down Up
Pro/Anti Pro
Funtion Description Researchers have analysed miRNA levels in Zmpste24-deficient mice, a model of Hutchinson-Gilford progeria syndrome. We have found that expression of the miR-29 family of miRNAs is markedly upregulated in Zmpste24(-/-) progeroid mice as well as during norm
Regulation Gene NA
Year 2011
Pubmed ID 21522133
Title Aging and chronic DNA damage response activate a regulatory pathway involving miR-29 and p53.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA