| Name |
miR-29c-3p
|
| Type |
miRNA
|
| Species |
Homo sapiens
|
| Tissue |
bone
|
| Experiment Method |
qRCR,Western blot,IF,SASP,Dual luciferase reporter gene assay,SA-B-Gal assay
|
| Up/Down |
Up
|
| Pro/Anti |
Pro
|
| Funtion Description |
The over-expression of miR-29c-3p led to enhanced senescence-associated-B-galactosidase (SA-B-gal) staining, senescence associated secretory phenotype (SASP), senescence associated heterochromatic foci (SAHF), reduced proliferation ability, retarded osteo
|
| Regulation Gene |
CNOT6
|
| Year |
2016
|
| Pubmed ID |
26792405
|
| Title |
miR-29c-3p promotes senescence of human mesenchymal stem cells by targeting CNOT6 through p53-p21 and p16-pRB pathways.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|