A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-30
Type miRNA
Species Mus musculus
Tissue NA
Experiment Method Western blot ,quantitative Real-Time PCR,Luciferase reporter assay,ChIP,Northern blotting,SA-B-Gal staining
Up/Down Up
Pro/Anti anti
Funtion Description miR-30 inhibits both p16INK4A and p53, 2 key senescence effectors, leading to efficient senescence disruption.
Regulation Gene CHD7,TNRC6A
Year 2018
Pubmed ID 29907771
Title miR-30 disrupts senescence and promotes cancer by targeting both p16INK4A and DNA damage pathways.
Drug NA
Disease cancer
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA