| Name |
miR-30a
|
| Type |
miRNA
|
| Species |
Homo sapiens
|
| Tissue |
skin
|
| Experiment Method |
real-time quantitative PCR,Microarray,western blotting,luciferase assays,
|
| Up/Down |
Up
|
| Pro/Anti |
Pro
|
| Funtion Description |
Stable MiR-30a over-expression strongly impaired epidermal differentiation, inducing severe barrier function defects in an organotypic culture model. A significant increase was also observed in the level of apoptotic cells in epidermis over-expressing miR
|
| Regulation Gene |
LOX,IDH1,AVEN
|
| Year |
2017
|
| Pubmed ID |
29165315
|
| Title |
An expression screen for aged-dependent microRNAs identifies miR-30a as a key regulator of aging features in human epidermis.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|