A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-31
Type miRNA
Species Homo sapiens
Tissue breast
Experiment Method Luciferase Assays,Western Blot,Quantitative RT-PCR, ChIP
Up/Down Down
Pro/Anti anti
Funtion Description Our data suggest that miR-31 is an important physiological target of HDACi, and that it is an important regulator of senescence relevant to cancer. These studies further suggest that manipulation of miR-31 expression can be used to modulate senescence-rel
Regulation Gene BMI1
Year 2015
Pubmed ID 25737447
Title MicroRNA-31 is a transcriptional target of histone deacetylase inhibitors and a regulator of cellular senescence.
Drug NA
Disease breast cancer
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA