| Name |
miR-31a-5p
|
| Type |
miRNA
|
| Species |
Mus musculus
|
| Tissue |
bone
|
| Experiment Method |
Immunofluorescence,Cell senescence-associated B-galactosidase staining,assay,Quantitative Real-time PCR Western blot
|
| Up/Down |
Up
|
| Pro/Anti |
NA
|
| Funtion Description |
miR-31a-5p was significantly increased with the aging of BMSCs and was secreted into the extracellular microenvironment via exosomes. Then, miR-31a-5p, using exosomes as vehicles, not only regulated BMSCs function in osteogenesis and cellular aging by the
|
| Regulation Gene |
SATB2
|
| Year |
2018
|
| Pubmed ID |
29896785
|
| Title |
MicroRNA-31a-5p from aging BMSCs links bone formation and resorption in the aged bone marrow microenvironment
|
| Drug |
NA
|
| Disease |
osteoporosis
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|