Details
| Name | CDC73 |
| Type | gene |
| Species | Homo sapiens |
| Tissue | 293T,;A549; HUVEC |
| Experiment Method | qRT-PCR;Western blot |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | Importantly, depletion of CDC73 could induce senescence-associated phenotypes in both normal and cancer cells, with an increase in p21 expression. In terms of molecular mechanism, alternative polyadenylation (APA)-mediated 3' untranslated region (3' UTR) |
| Regulation Gene | NA |
| Year | 2018 |
| Pubmed ID | 29621547 |
| Title | Down-regulation of cancer-associated gene CDC73 contributes to cellular senescence. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |