| Name |
miR-335
|
| Type |
miRNA
|
| Species |
Homo sapiens
|
| Tissue |
NA
|
| Experiment Method |
Luciferase reporter assay,miRNA and gene expression assays,Western blot
|
| Up/Down |
Up
|
| Pro/Anti |
NA
|
| Funtion Description |
We identified a microRNA, miR-335, up-regulated in the senescent normal fibroblasts and CAF and able to modulate the secretion of SASP factors and induce cancer cell motility in co-cultures, at least in part by suppressing the expression of phosphatase an
|
| Regulation Gene |
PTEN
|
| Year |
2016
|
| Pubmed ID |
27385366
|
| Title |
A miR-335/COX-2/PTEN axis regulates the secretory phenotype of senescent cancer-associated fibroblasts
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|