| Name |
miR-335
|
| Type |
miRNA
|
| Species |
Homo sapiens
|
| Tissue |
NA
|
| Experiment Method |
RNAi,Senescence-associated B-galactosidase assay (SA-B-gal),Luciferase reporter assay,qRT-PCR,Western blotting
|
| Up/Down |
NA
|
| Pro/Anti |
anti
|
| Funtion Description |
We demonstrate that the latter accounted for inhibition of 5-Aza-dC incorporation into the cell genome, enabling them to escape from induction of senescence. We also report that CARF (Collaborator of ARF) is a new target of miR-335 that regulates its grow
|
| Regulation Gene |
CARF
|
| Year |
2016
|
| Pubmed ID |
27457128
|
| Title |
Loss-of-function screening to identify miRNAs involved in senescence: tumor suppressor activity of miRNA-335 and its new target CARF
|
| Drug |
5-Aza-dC
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|