| Name |
miR-335
|
| Type |
miRNA
|
| Species |
Mus musculus
|
| Tissue |
bone
|
| Experiment Method |
Real-time quantitative PCR,NMA,Immunofluorescence,Western blot
|
| Up/Down |
Up
|
| Pro/Anti |
Pro
|
| Funtion Description |
Forced expression of miR-335 resulted in early senescence-like alterations in hMSCs, including: increased SA-B-gal activity and cell size, reduced cell proliferation capacity, augmented levels of p16 protein, and the development of a senescent-associated
|
| Regulation Gene |
NA
|
| Year |
2014
|
| Pubmed ID |
24648336
|
| Title |
miR-335 correlates with senescence/aging in human mesenchymal stem cells and inhibits their therapeutic actions through inhibition of AP-1 activity.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|