A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-335-3p
Type miRNA
Species Mus musculus
Tissue brain
Experiment Method RNA immunoprecipitation,qPCR,Western blot,Luciferase reporter assay
Up/Down Up
Pro/Anti NA
Funtion Description Deficiency of miR-335-3p in hippocampal brain leads to increased cellular cholesterol and improved spatial learning and memory.
Regulation Gene hmgcs1,sfrs2
Year 2018
Pubmed ID 30125687
Title The age-dependent elevation of miR-335-3p leads to reduced cholesterol and impaired memory in brain
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA