| Name |
miR-338-5p
|
| Type |
miRNA
|
| Species |
Homo sapiens
|
| Tissue |
NA
|
| Experiment Method |
RT-qPCR,Dual luciferase reporter gene assay,Western blot,MTT,BGalactosidase staining,microarray
|
| Up/Down |
Down
|
| Pro/Anti |
Pro
|
| Funtion Description |
We found that overexpression of miR-338-5p suppresses glioma cell proliferation, migration, and invasion and accelerates its senescence and apoptosis by decreasing FOXD1 expression via inhibition of activation of MAPK-signaling pathway.
|
| Regulation Gene |
FOXD1
|
| Year |
2018
|
| Pubmed ID |
30225541
|
| Title |
MicroRNA-338-5p plays a tumor suppressor role in glioma through inhibition of the MAPK-signaling pathway by binding to FOXD1.
|
| Drug |
NA
|
| Disease |
glioma
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|