Details
| Name | miR-339-5p |
| Type | miRNA |
| Species | Homo sapiens |
| Tissue | colorectal |
| Experiment Method | luciferase reporter assays,Western-blot,Real-Time PCR |
| Up/Down | Down |
| Pro/Anti | Pro |
| Funtion Description | Through the down-regulation of MDM2, microRNA-339-5p increases p53 protein levels and functions, including p53 transcriptional activity and p53-mediated apoptosis and senescence in response to stress. Furthermore, microRNA-339-5p inhibits the migration an |
| Regulation Gene | MDM2 |
| Year | 2015 |
| Pubmed ID | 25193859 |
| Title | MicroRNA-339-5p inhibits colorectal tumorigenesis through regulation of the MDM2/p53 signaling. |
| Drug | H2O2 |
| Disease | colorectal cancer |
| Environment Factors | oxidation |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |