A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-342-5p
Type miRNA
Species Mus musculus
Tissue NA
Experiment Method Senescence-associated B-galactosidase (SA-B-Gal) staining,MTT ,Western blotting,Dual luciferase assay,qPCR
Up/Down Down
Pro/Anti anti
Funtion Description Downregulated miR-342-5p is involved in regulating cell proliferation and cell cycles in Zmpste24/ MEFs by suppressing GAS2 in vitro.
Regulation Gene GAS2
Year 2017
Pubmed ID 28990109
Title miR3425p promotes Zmpste24deficient mouse embryonic fibroblasts proliferation by suppressing GAS2.
Drug NA
Disease Hutchinson-Gilford progeria syndrome
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA