A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-34a
Type miRNA
Species Homo sapiens
Tissue brain
Experiment Method RT-qPCR,Western blotting,SenescenceassociatedBgalactosidase (SABgal) assay
Up/Down Up
Pro/Anti Pro
Funtion Description upregulation of miR34a induced DNA damage, shortened telomere length and impaired telomerase activity.
Regulation Gene sirt1
Year 2019
Pubmed ID 30592284
Title miR34a derived from mesenchymal stem cells stimulates senescence in glioma cells by inducing DNA damage.
Drug NA
Disease glioma
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA