A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-34a
Type miRNA
Species Homo sapiens
Tissue lung
Experiment Method Senescence-associated B-galactosidase (SA-B-gal) staining,Western blot
Up/Down NA
Pro/Anti Pro
Funtion Description More importantly, our studies have revealed that knockdown of Myc expression recapitulates the senescence-promoting effects of miR-34a and augments IR-induced cell killing in NSCLC cells. These new findings demonstrate for the first time that pharmacologi
Regulation Gene Myc
Year 2017
Pubmed ID 29050242
Title MiR-34a modulates ionizing radiation-induced senescence in lung cancer cells.
Drug NA
Disease lung cancer
Environment Factors ionizing radiation
Circulating NA
Variant NA
High-throughput NA