Details
| Name | miR-34a |
| Type | miRNA |
| Species | Homo sapiens |
| Tissue | lung |
| Experiment Method | Real-time PCR,Western blotting |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | In summary, we found that miR-34a upregulation in AECs of aged animals promoted dysfunctions of these cells by inducing cellular senescence, mitochondrial aberration, and cell death and thus leading to pulmonary fibrosis in the aged population. |
| Regulation Gene | Sirt1,E2F3,E2 |
| Year | 2017 |
| Pubmed ID | 27979858 |
| Title | miR-34a promotes fibrosis in aged lungs by inducing alveolarepithelial dysfunctions |
| Drug | NA |
| Disease | fibrosis in aged lungs |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |