Details
| Name | miR-34a |
| Type | miRNA |
| Species | Mus musculus |
| Tissue | lung |
| Experiment Method | Quantitative Real-Time Polymerase Chain Reaction,Western Blotting |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | Mechanistically, we found that miR-34a induced a senescent phenotype in lung fibroblasts because this microRNA increased senescence-associated B-galactosidase activity, enhanced expression of senescence markers, and decreased cell proliferative capacities |
| Regulation Gene | Sirt1,E2,D1,E2F3 |
| Year | 2017 |
| Pubmed ID | 27635790 |
| Title | miR-34a Inhibits Lung Fibrosis by Inducing Lung Fibroblast Senescence. |
| Drug | NA |
| Disease | fibrosis in aged lungs |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |