A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-34a
Type miRNA
Species Mus musculus
Tissue ear
Experiment Method q-PCR
Up/Down Up
Pro/Anti NA
Funtion Description In the present study, we identified concordant increases in miR-34a levels in the cochlea, auditory cortex, and plasma of C57BL/6 mice during aging. These increases were accompanied by elevated hearing thresholds and greater loss of hair cells. Levels of
Regulation Gene SIRT1,Bcl-2,E2F3
Year 2016
Pubmed ID 26802970
Title Circulating miR-34a levels correlate with age-related hearing loss in mice and human
Drug NA
Disease age-related hearing loss
Environment Factors NA
Circulating plasma
Variant NA
High-throughput NA