| Name |
miR-34a
|
| Type |
miRNA
|
| Species |
Mus musculus
|
| Tissue |
bone
|
| Experiment Method |
qRT-PCR,Senescence-associated B-galactosidase staining,western blot
|
| Up/Down |
NA
|
| Pro/Anti |
Pro
|
| Funtion Description |
The results of the current study showed that miR-34a was significantly up-regulated under H/SD conditions in MSCs, while overexpression of miR-34a was significantly associated with increased apoptosis, impaired cell vitality and aggravated senescence. Mor
|
| Regulation Gene |
SIRT1
|
| Year |
2015
|
| Pubmed ID |
26446137
|
| Title |
Roles of microRNA-34a targeting SIRT1 in mesenchymal stem cells.
|
| Drug |
NA
|
| Disease |
Ischemic heart disease (IHD)
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|