A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-34a
Type miRNA
Species Homo sapiens
Tissue Lens epithelium
Experiment Method RT-PCR
Up/Down Up
Pro/Anti Pro
Funtion Description MicroRNA 34a (miR-34a) is involved in regulating tissue senescence.. miR-34a expression levels were significantly different between each age group, and there were moderate correlations between high NC, C, and P cataract scores and high miR-34a levels . Th
Regulation Gene p53
Year 2013
Pubmed ID 23661155
Title Correlation between microRNA-34a levels and lens opacity severity in age-related cataracts
Drug silent information regulator T1 (SirT1)
Disease Cataracts
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA