A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name CDK
Type gene
Species Mus musculus
Tissue NA
Experiment Method PCR,other
Up/Down Down
Pro/Anti NA
Funtion Description Researchers generated transgenic mice that permit conditional p16 expression. Broad induction at weaning inhibited proliferation of intestinal transit-amplifying and Lgr6+ stem cells and rapidly imposed features of aging, including hair loss, skin wrinkli
Regulation Gene NA
Year 2015
Pubmed ID 25481981
Title Reversible cell cycle inhibition and premature aging features imposed by conditional expression of p16Ink4a.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant 1
High-throughput NA