Details
| Name | miR-34a |
| Type | miRNA |
| Species | Homo sapiens |
| Tissue | HEK293;HUVEC |
| Experiment Method | RT-PCR,Western Blot |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | The overexpression of miRNA-34a down regulated mRNA and protein level of SIRT1 in HEK293-miRNA-34a and HUVEC-miRNA-34a cell groups. Comet assay revealed that HUVEC-miRNA-34a cell group was the most sensitive to H2O2 treatment, and the DNA damage of HUVEC- |
| Regulation Gene | SIRT1 |
| Year | 2013 |
| Pubmed ID | 23600198 |
| Title | Research on regulation of cell senescence by miRNA-34a |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |