A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-34a
Type miRNA
Species Mus musculus
Tissue Liver
Experiment Method qPCR
Up/Down Up
Pro/Anti Anti
Funtion Description A model of post-transcriptional repression, not only of genes involved in oxidative stress regulation and oxidative stress defense proteins, such as Sirt1 and Mgst1, but also of upstream transcription factors (TFs) regulating their activation, since Sp1 i
Regulation Gene Sp1;Nrf2(Nfe2l2);Sirt1;Mgst1
Year 2011
Pubmed ID 21216258
Title Increased expression of miR-34a and miR-93 in rat liver during aging, and their impact on the expression of Mgst1 and Sirt1.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA