A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-34a
Type miRNA
Species Homo sapiens
Tissue HUVECs ;HAEC;HMVEC
Experiment Method RT-PCR,Western Blot
Up/Down Up
Pro/Anti Pro
Funtion Description Endothelial senescence is thought to play a role in cardiovascular diseases such as atherosclerosis. We hypothesized that endothelial microRNAs (miRNAs) regulate endothelial survival and senescence. We found that miR-34a is highly expressed in primary end
Regulation Gene SIRT1
Year 2010
Pubmed ID 20627091
Title MicroRNA-34a regulation of endothelial senescence
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA