A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-34a
Type miRNA
Species Homo sapiens
Tissue HCT 116
Experiment Method RT-PCR
Up/Down Up
Pro/Anti Pro
Funtion Description MiR-34a was highly up-regulated in a human colon cancer cell line, HCT 116, treated with a DNA-damaging agent, adriamycin. Transient introduction of miR-34a into two human colon cancer cell lines, HCT 116 and RKO, caused complete suppression of cell proli
Regulation Gene NA
Year 2007
Pubmed ID 17875987
Title Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA