| Name |
miR-34c-5p
|
| Type |
miRNA
|
| Species |
Homo sapiens
|
| Tissue |
HA-VSMCs
|
| Experiment Method |
qRT-PCR,SA-B-gal staining,Alizarin Red S staining,Western blot,Luciferase reporter assay,RNA RIP
|
| Up/Down |
Down
|
| Pro/Anti |
anti
|
| Funtion Description |
MiR-34c-5p, not miR-34c-3p, was suppressed significantly in calcification/senescence of human aorta vascular smooth muscle cells (HA-VSMCs) induced by high glucose, which was proven by the formation of mineralized nodules and staining of senescence associ
|
| Regulation Gene |
BMF
|
| Year |
2019
|
| Pubmed ID |
30654331
|
| Title |
lncRNA-ES3/miR-34c-5p/BMF axis is involved in regulating high-glucose-induced calcification/senescence of VSMCs.
|
| Drug |
NA
|
| Disease |
Vascular calcification (VC)
|
| Environment Factors |
high glucose
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|