A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name CDK2AP1
Type gene
Species Homo sapiens
Tissue fibroblasts
Experiment Method PCR, western blot
Up/Down NA
Pro/Anti Anti
Funtion Description we found that knockdown of CDK2AP1 in primary human fibroblasts resulted in reduced proliferation and in the induction of senescence associated beta-galactosidase activity. CDK2AP1 knockdown also resulted in a significant reduction in the percentage of ce
Regulation Gene NA
Year 2015
Pubmed ID 25785833
Title Knockdown of CDK2AP1 in primary human fibroblasts induces p53 dependent senescence
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA