A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-35a
Type miRNA
Species Homo sapiens
Tissue HEKn
Experiment Method qRT-PCR
Up/Down Up
Pro/Anti Pro
Funtion Description Keratinocyte replicative senescence has an important role in time-dependent changes of the epidermis, a tissue with high turnover. Senescence encompasses growth arrest during which cells remain metabolically active but acquire a typical enlarged, vacuolar
Regulation Gene SATB1;CDK6 30 UTRs
Year 2012
Pubmed ID 22683624
Title MicroRNA-191 triggers keratinocytes senescence by SATB1 and CDK6 downregulation
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA