A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-370
Type miRNA
Species Homo sapiens
Tissue HL60;K562
Experiment Method qRT-PCR,Western Blot
Up/Down Down
Pro/Anti Pro
Funtion Description We found that the down-regulation of miR-370 expression was a frequent event in both leukemia cell lines and primary leukemic cells from patients with de novo AML. Lower levels of miR-370 expression were found in 37 of 48 leukemic samples from AML patient
Regulation Gene FoxM1
Year 2012
Pubmed ID 22900969
Title The tumor suppressive role of miRNA-370 by targeting FoxM1 in acute myeloid leukemia
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA