Details
| Name | miR-375 |
| Type | miRNA |
| Species | Homo sapiens |
| Tissue | K562 |
| Experiment Method | RT-PCR |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | MicroRNA profiling revealed upregulatedmiR-375in DOX-induced senescent K562 cells. Treatment withmiR-375inhibitor was able to reverse the proliferation ability suppressed by DOX and overexpression ofmiR-375suppressed the normal proliferation of K562 cells |
| Regulation Gene | 4-3-3zeta;SP1 |
| Year | 2012 |
| Pubmed ID | 22606351 |
| Title | Induction of Cellular Senescence by Doxorubicin Is Associated with UpregulatedmiR-375and Induction of Autophagy in K562 Cells |
| Drug | doxorubicin |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |