| Name |
miR-377
|
| Type |
miRNA
|
| Species |
Homo sapiens
|
| Tissue |
skin
|
| Experiment Method |
SA-B-gal staining,MTS,Luciferase reporter assays,RT-qPCR
|
| Up/Down |
Up
|
| Pro/Anti |
Pro
|
| Funtion Description |
miR-377 overexpression promoted senescence in young HSFs, and inhibition of miR-377 reduced senescence in passage-aged HSFs.
|
| Regulation Gene |
DNA methyltransferase 1
|
| Year |
2017
|
| Pubmed ID |
28277545
|
| Title |
miR-377 induces senescence in human skin fibroblasts by targeting DNA methyltransferase 1.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
UVA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|