A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-384-5p
Type miRNA
Species Mus musculus
Tissue bone
Experiment Method qRT-PCR,dual luciferase assay
Up/Down Up
Pro/Anti anti
Funtion Description we demonstrated that miR-384-5p inhibited the expression of Gli2 both at the mRNA and protein levels by directly binding to the 3' untranslated region (3'UTR) of Gli2 mRNA.
Regulation Gene gli2
Year 2019
Pubmed ID 30950325
Title miR-384-5p targets Gli2 and negatively regulates age-related osteogenic differentiation of rat bone marrow mesenchymal stem cells.
Drug NA
Disease age-related osteoporosis
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA