| Name |
miR-449
|
| Type |
miRNA
|
| Species |
Mus musculus
|
| Tissue |
Gastric
|
| Experiment Method |
Western Blot
|
| Up/Down |
Down
|
| Pro/Anti |
Pro
|
| Funtion Description |
Growth rate of gastric cell lines over-expressing miR-449 was inhibited by 60% compared to controls. FACS cell cycle analysis of miR-449 over-expressing cells showed a significant increase in the sub-G1 fraction indicative of apoptosis. -Gal assays indica
|
| Regulation Gene |
GMNN;MET;CCNE2;SIRT1;CDK6
|
| Year |
2011
|
| Pubmed ID |
21418558
|
| Title |
miR-449 inhibits cell proliferation and is down-regulated in gastric cancer.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|