Details
| Name | 15-LOX2sv-b |
| Type | alternative splicing |
| Species | Homo sapiens |
| Tissue | prostate |
| Experiment Method | RT-PCR |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | First, the 15-LOX2 promoter activity and the mRNA and protein levels of 15-LOX2 and its multiple splice variants are upregulated in serially passaged NHP cells, which precede replicative senescence and occur in a cell-autonomous manner. |
| Regulation Gene | 15-LOX4 |
| Year | 2005 |
| Pubmed ID | 15750631 |
| Title | Cell-autonomous induction of functional tumor suppressor 15-lipoxygenase 2 (15-LOX4) contributes to replicative senescence of human prostate progenitor cells |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |