A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-451
Type miRNA
Species Homo sapiens
Tissue NA
Experiment Method qRT-PCR,Luciferase reporter assay,Western blotting,Immunostaining
Up/Down Down
Pro/Anti Pro
Funtion Description We report that miR-451 caused growth arrest in cells leading to their resistance to 5-Aza-dC-induced senescence.
Regulation Gene CARF
Year 2018
Pubmed ID 29321561
Title Tumor suppressor activity of miR-451: Identification of CARF as a new target
Drug 5-Aza-dC
Disease cancer
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA