A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-486-5p
Type miRNA
Species Homo sapiens
Tissue Abdominoplasty Superfluous Materials
Experiment Method RT-PCR,Western blot,Northern blot
Up/Down Up
Pro/Anti Pro
Funtion Description the expression of miR-486-5p is progressively expressed in human adipose tissue-derived mesenchymal stem cells (hATMSCs) with aging. Overexpression of miR-486-5p induces a premature senescence-like phenotype and inhibits proliferation of hAT-MSCs and inhi
Regulation Gene SIRT1
Year 2012
Pubmed ID 21988232
Title miR-486-5p Induces Replicative Senescence of Human Adipose Tissue-Derived Mesenchymal Stem Cells and Its Expression Is Controlled by High Glucose
Drug NA
Disease NA
Environment Factors High Glucose
Circulating NA
Variant NA
High-throughput NA