A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-494
Type miRNA
Species Homo sapiens
Tissue A549
Experiment Method RT-PCR,Western Blot
Up/Down Up
Pro/Anti Pro
Funtion Description Through comparison between miR-494 expressing cells and control cells, we revealed that miR-494 suppressed cell proliferation and colony forming activity, and induced senescence. Reporter activity was inhibited by miR-494. In addition, IGF2BP1 mRNA levels
Regulation Gene NA
Year 2011
Pubmed ID 22151897
Title MicroRNA-494 suppresses cell proliferation and induces senescence in A549 lung cancer cells.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA