A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-519
Type miRNA
Species Homo sapiens
Tissue HDFs
Experiment Method qPCR
Up/Down Up
Pro/Anti Pro
Funtion Description Overexpression of miR-519a in either WI-38 or human cervical carcinoma HeLa cells triggered senescence, as measured by monitoring B-galactosidase activity and other senescence markers. These data suggest that miR-519 can suppress tumor growth by triggerin
Regulation Gene NA
Year 2010
Pubmed ID 20606251
Title MicroRNA profiling in human diploid fibroblasts uncovers miR-519 role in replicative senescence
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA