A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-520c-3p
Type miRNA
Species Homo sapiens
Tissue NA
Experiment Method Microarray Data Analysis,RT-qPCR,Western Blot
Up/Down Up
Pro/Anti Pro
Funtion Description Here, we established that elevated miR-520c-3p represses global translation, cell proliferation and initiates premature senescence in HeLa and DLBCL cells. Moreover, we demonstrate that miR-520c-3p directly targets translation initiation factor, eIF4GII m
Regulation Gene eIF4GII
Year 2014
Pubmed ID 24497838
Title Down-regulation of eIF4GII by miR-520c-3p represses diffuse large B cell lymphoma development.
Drug NA
Disease diffuse large B-cell lymphoma (DLBCL),Human cervical carcinoma HeLa
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA